\[\boxed{\mathbf{339}.}\]
\[x^{4} + x^{2}y^{2} + y^{4} = \left( x^{2} \right)^{2} +\]
\[+ 2x^{2}y^{2} + \left( y^{2} \right)^{2} - 2x^{2}y^{2} +\]
\[+ x^{2}y^{2} =\]
\[= \left( x^{2} + y^{2} \right)^{2} - x^{2}y^{2} =\]
\[= \left( x^{2} + y^{2} - xy \right)\left( x^{2} + y^{2} + xy \right).\]