\[\boxed{\mathbf{186}.}\]
\[a_{6} = - 10;\ \ a_{16} = - 6:\]
\[a_{6} = a_{1} + 5d \rightarrow a_{1} = a_{6} - 5d =\]
\[= - 10 - 5d;\]
\[a_{16} = a_{1} + 15d \rightarrow a_{1} = a_{16} -\]
\[- 15d = - 6 - 15d.\]
\[- 10 - 5d = - 6 - 15d\]
\[10d = 4\]
\[d = 0,4.\]
\[a_{1} = - 10 - 5 \cdot 0,4 = - 10 -\]
\[- 2 = - 12.\]
\[S_{6} = \frac{a_{1} + a_{6}}{2} \cdot 6 =\]
\[= ( - 10 - 12) \cdot 3 =\]
\[= - 22 \cdot 3 = - 66.\]
\[Ответ:\ - 66.\]