\[(x + 2y)^{2} - (x - 2y)^{2} =\]
\[= x^{2} + 4xy + 4y^{2} - \left( x^{2} - 4xy + 4y^{2} \right) =\]
\[= x^{2} + 4xy + 4y^{2} - x^{2} + 4xy - 4y^{2} =\]
\[= 8xy\text{.\ }\]