\[(4x - 3y)^{2} - (2x + y)(3x - 5y) =\]
\[= 16x^{2} - 24xy + 9y^{2} - 6x^{2} + 10xy -\]
\[- 3xy + 5y^{2} = 10x^{2} - 17xy + 14y^{2}\text{.\ }\]