\[\boxed{\text{4.\ 280}}\]
\[\textbf{а)} - \frac{4}{5} \cdot \frac{5}{8} = - \frac{1}{2}\]
\[\textbf{б)}\ \frac{2}{12} \cdot \left( - \frac{3}{8} \right) = - \frac{1}{16}\]
\[\textbf{в)} - \frac{4}{9} \cdot \left( - \frac{15}{26} \right) = \frac{4 \cdot 15}{9 \cdot 26} =\]
\[= \frac{2 \cdot 5}{3 \cdot 13} = \frac{10}{39}\]
\[\textbf{г)} - \frac{7}{15} \cdot \left( - \frac{9}{14} \right) = \frac{7 \cdot 9}{15 \cdot 14} =\]
\[= \frac{3}{5 \cdot 2} = \frac{3}{10} = 0,3\]
\[\textbf{д)} - \frac{5}{12} \cdot 18 = - \frac{5 \cdot 3}{2} = - \frac{15}{2} =\]
\[= - 7,5\]
\[\textbf{е)} - 10 \cdot \left( - \frac{7}{10} \right) = 7\]