\[\frac{2^{5} \cdot {0,5}^{- 6}}{16^{3}} = \frac{2^{5} \cdot \left( \frac{1}{2} \right)^{- 6}}{\left( 2^{4} \right)^{3}} =\]
\[= \frac{2^{5} \cdot 2^{6}}{2^{12}} = \frac{2^{11}}{2^{12}} = \frac{1}{2} = 0,5.\]